The ageing immune system

Djukic M, Nau R, Sieber C (2014)

Publication Type: Journal article

Publication year: 2014

Journal

Deutsche Medizinische Wochenschrift Georg Thieme Verlag

Publisher: Georg Thieme Verlag

Book Volume: 139

Pages Range: 1987-90

Journal Issue: 40

DOI: 10.1055/s-0034-1370283

Abstract

The aging of the immune system, also called immunosenescence, contributes to the increased morbidity and mortality from infections, autoimmune diseases and cancer as well as to the low efficacy of vaccination in elderly persons. Immunosenescence is characterized by a decrease in cell-mediated immune function and by reduced humoral immune responses caused by age-related changes in the innate immune system and age-dependent defects in T-and B-cell function. This paper gives an overview of the most important modifications in the different compartments of the immune system during the ageing process.

Authors with CRIS profile

Cornel Sieber Lehrstuhl für Innere Medizin (Geriatrie)

Involved external institutions

Universitätsklinikum Göttingen DE Germany (DE)

How to cite

APA:

Djukic, M., Nau, R., & Sieber, C. (2014). The ageing immune system. Deutsche Medizinische Wochenschrift, 139(40), 1987-90. https://doi.org/10.1055/s-0034-1370283

MLA:

Djukic, M., R. Nau, and Cornel Sieber. "The ageing immune system." Deutsche Medizinische Wochenschrift 139.40 (2014): 1987-90.

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