Experimental validation of a new integrated simulated moving bed process for the production of single enantiomers

García Palacios J, Kramer B, Kienle A, Kaspereit M (2011)


Publication Language: English

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2011

Journal

Publisher: Elsevier

Book Volume: 1218

Pages Range: 2232-2239

Journal Issue: 16

DOI: 10.1016/j.chroma.2011.02.021

Abstract

A new integrated 3-zone simulated moving bed (SMB) concept with internal racemization reaction was suggested recently for the production of single enantiomers from racemic mixtures [1,2]. The process utilizes an internal gradient to trigger the racemization within a single zone. It can deliver the pure enantiomer and outperforms conventional technologies. In this contribution, the concept is validated experimentally for the separation of a model system compound. The results demonstrate that the new concept is capable of producing a single enantiomer with purity, yield and conversion of 100%. © 2011 Elsevier B.V.

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How to cite

APA:

García Palacios, J., Kramer, B., Kienle, A., & Kaspereit, M. (2011). Experimental validation of a new integrated simulated moving bed process for the production of single enantiomers. Journal of Chromatography A, 1218(16), 2232-2239. https://dx.doi.org/10.1016/j.chroma.2011.02.021

MLA:

García Palacios, Javier, et al. "Experimental validation of a new integrated simulated moving bed process for the production of single enantiomers." Journal of Chromatography A 1218.16 (2011): 2232-2239.

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