Development of new sol-gel derived Ag-doped biomaterials for dental applications

Chatzistavrou X, Kontonasaki E, Bakopoulou A, Theocharidou A, Sivropoulou A, Paraskevopoulos KM, Koidis P, Boccaccini AR, Kasuga T (2012)

Publication Status: Published

Publication Type: Conference contribution, Conference Contribution

Publication year: 2012

Book Volume: 1417

Pages Range: 41-46

Conference Proceedings Title: Materials Research Society

Event location: Boston, MA

ISBN: 9781627482295

DOI: 10.1557/opl.2012.743

Abstract

The aim of this work was to develop a new Ag-doped bioactive material with antibacterial behavior, optimizing the properties of the new fabricated composite material in the system SiO 58.6 -PO 7.2 -AlO 4.2 -CaO 24.9 -NaO 2.1 -KO 3 (wt%). Two systems with different concentrations in Ag O (Ba with 2.1 and Bb with 4.2 wt%) were prepared by the sol-gel method and compared to the respective silver-free control composite (CONTROL). The microstructural characteristics of the developed compositions were characterized by different techniques as UV/VIS spectroscopy, X-ray diffraction analysis (XRD) and Scanning Electron Microscopy with Energy Dispersive Spectroscopy (SEM-EDS). The antibacterial properties of the Ag-doped glass-ceramics were tested against the bacterial colony Staphylococcus aureus (S. aureus) which is very characteristic oral bacteria and the material-cell interaction was monitored in a primary culture of Human Gingival Fibroblasts (HGFs). Our study shows the successful incorporation of the silver ions in the ceramic structure and the preparation of new Ag-doped composite materials with cell-proliferation-inductive, as well as antibacterial properties indicating their potential application dental tissue restoration strategies. © 2012 Materials Research Society.

Authors with CRIS profile

Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Nagoya Institute of Technology / 名古屋工業大学 Nagoya Kōgyō Daigaku JP Japan (JP) Aristotle University of Thessaloniki GR Greece (GR)

How to cite

APA:

Chatzistavrou, X., Kontonasaki, E., Bakopoulou, A., Theocharidou, A., Sivropoulou, A., Paraskevopoulos, K.M.,... Kasuga, T. (2012). Development of new sol-gel derived Ag-doped biomaterials for dental applications. In Materials Research Society (pp. 41-46). Boston, MA.

MLA:

Chatzistavrou, Xanthippi, et al. "Development of new sol-gel derived Ag-doped biomaterials for dental applications." Proceedings of the 2011 MRS Fall Meeting, Boston, MA 2012. 41-46.

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