How the Structural elucidation of the natural product Stephanosporin led to new developments in aryl radical and medicinal chemistry

Fehler S, Heinrich M (2015)


Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2015

Journal

Publisher: Georg Thieme Verlag

Book Volume: 26

Pages Range: 580-603

Article Number: st-2014-a0923-a

Journal Issue: 5

DOI: 10.1055/s-0034-1378945

Abstract

The intent of this account is to provide a focused overview of recent developments in aryl radical chemistry, especially extensions and applications of the Meerwein arylation and the Gomberg-Bachmann reaction. Although most of the reactions and methods described were discovered on the basis of earlier findings made by our group or logically depend on newly discovered reactivities or mechanistic principles, the rapid evolution of radical chemistry can nevertheless be traced back to the behavior of the natural product stephanosporin, which is capable of liberating 2-chloro-4-nitrophenol via an aryl radical intermediate.

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How to cite

APA:

Fehler, S., & Heinrich, M. (2015). How the Structural elucidation of the natural product Stephanosporin led to new developments in aryl radical and medicinal chemistry. Synlett, 26(5), 580-603. https://dx.doi.org/10.1055/s-0034-1378945

MLA:

Fehler, Stefanie, and Markus Heinrich. "How the Structural elucidation of the natural product Stephanosporin led to new developments in aryl radical and medicinal chemistry." Synlett 26.5 (2015): 580-603.

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