Mechanical properties and drug release behavior of PCL/zein coated 45S5 bioactive glass scaffolds for bone tissue engineering application

Fereshteh Z, Nooeaid P, Fathi M, Bagri A, Boccaccini AR (2015)

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2015

Journal

Data in Brief Elsevier

Book Volume: 4

Pages Range: 524-528

DOI: 10.1016/j.dib.2015.07.013

Abstract

This article presents data related to the research article entitled "The effect of coating type on mechanical properties and controlled drug release of PCL/zein coated 45S5 bioactive glass scaffolds for bone tissue engineering" [1]. We provide data on mechanical properties, in vitro bioactivity and drug release of bioactive glass (BG) scaffolds coated by poly (. ε-caprolactone) (PCL) and zein used as a controlled release device for tetracycline hydrochloride (TCH). By coating the BG scaffolds with PCL or PCL/zein blend the mechanical properties of the scaffolds were substantially improved, i.e., the compressive strength increased from 0.004±0.001. MPa (uncoated BG scaffolds) to 0.15±0.02. MPa (PCL/zein coated BG scaffolds). A dense bone-like apatite layer formed on the surface of PCL/zein coated scaffolds immersed for 14 days in simulated body fluid (SBF). The data describe control of drug release and in vitro degradation behavior of coating by engineering the concentration of zein. Thus, the developed scaffolds exhibit attractive properties for application in bone tissue engineering research.

Authors with CRIS profile

Patcharakamon Nooeaid Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Massachusetts Institute of Technology (MIT) US United States (USA) (US) Isfahan University of Technology (IUT) / دانشگاه صنعتی اصفهان IR Iran, Islamic Republic of (IR)

How to cite

APA:

Fereshteh, Z., Nooeaid, P., Fathi, M., Bagri, A., & Boccaccini, A.R. (2015). Mechanical properties and drug release behavior of PCL/zein coated 45S5 bioactive glass scaffolds for bone tissue engineering application. Data in Brief, 4, 524-528. https://dx.doi.org/10.1016/j.dib.2015.07.013

MLA:

Fereshteh, Zeinab, et al. "Mechanical properties and drug release behavior of PCL/zein coated 45S5 bioactive glass scaffolds for bone tissue engineering application." Data in Brief 4 (2015): 524-528.

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