Roether J, Rai R, Wolf R, Tallawi M, Boccaccini AR (2014)
Publication Status: Published
Publication Type: Journal article, Original article
Publication year: 2014
Publisher: Maney Publishing
Book Volume: 30
Pages Range: 574-581
Journal Issue: 5
DOI: 10.1179/1743284713Y.0000000499
Novel Nanocomposite films containing TiO2 nanoparticles incorporated in blend matrices of biocompatible and bioresorbable polymers, namely poly(glycerol sebacate) (PGS) and poly(3-hydroxybutyrate) P(3HB), were developed. The samples were fabricated via a sequential step of solvent casting followed by cross-linking. PGS/P(3HB) blends (controls) were fabricated in two different ratios, i.e. 7 : 1 and 8 : 1. Varying amounts of TiO2 nanoparticles (1 and 2 vol.-%) were incorporated into the matrices. SEM studies revealed that the TiO2 particles were distributed both within the matrix and on the surface of the films thus imparting surface nanotopography and increasing the surface roughness. These microstructural features combined with the cumulative effect of blending of the two polymeric systems influenced the wettability, chemical and mechanical properties of the films. In vitro degradation of the fabricated matrices in PBS medium over a 30 day period confirmed that the composites undergo weight loss and mechanical, chemical and surface topography changes. The nanocomposites constitute model biodegradable organic-inorganic systems suitable for tissue engineering applications.
APA:
Roether, J., Rai, R., Wolf, R., Tallawi, M., & Boccaccini, A.R. (2014). Biodegradable poly(glycerol sebacate)/poly(3-hydroxybutyrate)-TiO2 nanocomposites: fabrication and characterisation. Materials Science and Technology, 30(5), 574-581. https://dx.doi.org/10.1179/1743284713Y.0000000499
MLA:
Roether, Judith, et al. "Biodegradable poly(glycerol sebacate)/poly(3-hydroxybutyrate)-TiO2 nanocomposites: fabrication and characterisation." Materials Science and Technology 30.5 (2014): 574-581.
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