Factors influencing relative speech intelligibility in patients with oral squamous cell carcinoma: a prospective study using automatic, computer-based speech analysis.

Stelzle F, Knipfer C, Schuster M, Bocklet T, Nöth E, Adler W, Schempf L, Vieler P, Riemann M, Neukam FW, Nkenke E (2013)

Publication Status: Published

Publication Type: Journal article

Publication year: 2013

Journal

International Journal of Oral and Maxillofacial Surgery Elsevier

Book Volume: 42

Pages Range: 1377-84

Journal Issue: 11

DOI: 10.1016/j.ijom.2013.05.021

Abstract

Oral squamous cell carcinoma (OSCC) and its treatment impair speech intelligibility by alteration of the vocal tract. The aim of this study was to identify the factors of oral cancer treatment that influence speech intelligibility by means of an automatic, standardized speech-recognition system. The study group comprised 71 patients (mean age 59.89, range 35-82 years) with OSCC ranging from stage T1 to T4 (TNM staging). Tumours were located on the tongue (n=23), lower alveolar crest (n=27), and floor of the mouth (n=21). Reconstruction was conducted through local tissue plasty or microvascular transplants. Adjuvant radiotherapy was performed in 49 patients. Speech intelligibility was evaluated before, and at 3, 6, and 12 months after tumour resection, and compared to that of a healthy control group (n=40). Postoperatively, significant influences on speech intelligibility were tumour localization (P=0.010) and resection volume (P=0.019). Additionally, adjuvant radiotherapy (P=0.049) influenced intelligibility at 3 months after surgery. At 6 months after surgery, influences were resection volume (P=0.028) and adjuvant radiotherapy (P=0.034). The influence of tumour localization (P=0.001) and adjuvant radiotherapy (P=0.022) persisted after 12 months. Tumour localization, resection volume, and radiotherapy are crucial factors for speech intelligibility. Radiotherapy significantly impaired word recognition rate (WR) values with a progression of the impairment for up to 12 months after surgery.

Authors with CRIS profile

Florian Stelzle Medizinische Fakultät Tobias Bocklet Professur für Informatik (Mustererkennung) Elmar Nöth Professur für Informatik (Mustererkennung) Werner Adler Lehrstuhl für Biometrie und Epidemiologie Peter Vieler Medizinische Fakultät Max Riemann Medizinische Fakultät Friedrich Wilhelm Neukam Lehrstuhl für Zahnmedizin, insbesondere Mund-, Kiefer-, und Gesichtschirurgie

Involved external institutions

Klinikum der Universität München (Großhadern und Innenstadt) DE Germany (DE)

How to cite

APA:

Stelzle, F., Knipfer, C., Schuster, M., Bocklet, T., Nöth, E., Adler, W.,... Nkenke, E. (2013). Factors influencing relative speech intelligibility in patients with oral squamous cell carcinoma: a prospective study using automatic, computer-based speech analysis. International Journal of Oral and Maxillofacial Surgery, 42(11), 1377-84. https://dx.doi.org/10.1016/j.ijom.2013.05.021

MLA:

Stelzle, Florian, et al. "Factors influencing relative speech intelligibility in patients with oral squamous cell carcinoma: a prospective study using automatic, computer-based speech analysis." International Journal of Oral and Maxillofacial Surgery 42.11 (2013): 1377-84.

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