Hopmann E, Arlt W, Minceva M (2011)
Publication Status: Published
Publication Type: Journal article
Publication year: 2011
Publisher: Elsevier
Book Volume: 1218
Pages Range: 242-250
Journal Issue: 2
DOI: 10.1016/j.chroma.2010.11.018
The aim of this investigation was to minimize the experimental effort for solvent system selection in counter-current chromatography. The separation mechanism in counter-current chromatography is based exclusively on the partitioning of the solute between the two liquid phases. Therefore, a quantum chemical method combined with statistical thermodynamics (conductor-like screening model for real solvents, COSMO-RS) was used for the prediction of the partition coefficient. A comparison of the experimental and predicted data for five model solutes systems demonstrated the potential of the use of COSMO-RS as a screening tool for the solvent system selection. (C) 2010 Elsevier B.V. All rights reserved.
APA:
Hopmann, E., Arlt, W., & Minceva, M. (2011). Solvent system selection in counter-current chromatography using conductor-like screening model for real solvents. Journal of Chromatography A, 1218(2), 242-250. https://dx.doi.org/10.1016/j.chroma.2010.11.018
MLA:
Hopmann, Elisabeth, Wolfgang Arlt, and Mirjana Minceva. "Solvent system selection in counter-current chromatography using conductor-like screening model for real solvents." Journal of Chromatography A 1218.2 (2011): 242-250.
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