Pipette aspiration applied to the characterization of nonhomogeneous, transversely isotropic materials used for vocal fold modeling

Weiß S, Thomson SL, Lerch R, Döllinger M, Sutor A (2013)

Publication Status: Published

Publication Type: Journal article

Publication year: 2013

Journal

Journal of the Mechanical Behavior of Biomedical Materials Elsevier

Publisher: Elsevier

Book Volume: 17

Pages Range: 137-151

DOI: 10.1016/j.jmbbm.2012.08.005

Abstract

The etiology and treatment of voice disorders are still not completely understood. Since the vibratory characteristics of vocal folds are strongly influenced by both anatomy and mechanical material properties, measurement methods to analyze the material behavior of vocal fold tissue are required. Due to the limited life time of real tissue in the laboratory, synthetic models are often used to study vocal fold vibrations. In this paper we focus on two topics related to synthetic and real vocal fold materials. First, because certain tissues within the human vocal folds are transversely isotropic, a fabrication process for introducing this characteristic in commonly used vocal fold modeling materials is presented. Second, the pipette aspiration technique is applied to the characterization of these materials. By measuring the displacement profiles of stretched specimens that exhibit varying degrees of transverse isotropy, it is shown that local anisotropy can be quantified using a parameter describing the deviation from an axisymmetric profile. The potential for this technique to characterize homogeneous, anisotropic materials, including soft biological tissues such as those found in the human vocal folds, is supplemented by a computational study. (c) 2012 Elsevier Ltd. All rights reserved.

Authors with CRIS profile

Sandra Weiß Lehrstuhl für Autonome Systeme und Mechatronik Reinhard Lerch Lehrstuhl für Autonome Systeme und Mechatronik Michael Döllinger Professur für Computational Medicine (DFG-Forschungsprofessur) Alexander Sutor Lehrstuhl für Autonome Systeme und Mechatronik

Involved external institutions

Brigham Young University US United States (USA) (US)

How to cite

APA:

Weiß, S., Thomson, S.L., Lerch, R., Döllinger, M., & Sutor, A. (2013). Pipette aspiration applied to the characterization of nonhomogeneous, transversely isotropic materials used for vocal fold modeling. Journal of the Mechanical Behavior of Biomedical Materials, 17, 137-151. https://doi.org/10.1016/j.jmbbm.2012.08.005

MLA:

Weiß, Sandra, et al. "Pipette aspiration applied to the characterization of nonhomogeneous, transversely isotropic materials used for vocal fold modeling." Journal of the Mechanical Behavior of Biomedical Materials 17 (2013): 137-151.

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