Effect of amorphous phases during the hydraulic conversion of alpha-TCP into calcium-deficient hydroxyapatite

Hurle K, Neubauer J, Bohner M, Döbelin N, Götz-Neunhoeffer F (2014)

Publication Language: English

Publication Type: Journal article

Publication year: 2014

Journal

Acta Biomaterialia Elsevier

Publisher: Elsevier

Book Volume: 10

Pages Range: 3931-3941

DOI: 10.1016/j.actbio.2014.03.017

Abstract

Powders of α-tricalcium phosphate (α-TCP), which readily react with water to form calcium-deficient hydroxyapatite (CDHA), are frequently used in bone cements. As, for clinical applications, it is important to adjust the setting reaction of the cements to a reasonable reaction time, exact knowledge of the hydration mechanism is essential. It is known that prolonged milling results in partial amorphization of α-TCP powders and that dissolution of the amorphous phase significantly accelerates the hydration, but it is not clear yet when the amorphous phase reacts in comparison to the crystalline α-TCP. Therefore the aim of this study was to investigate the development of quantitative phase content of α-TCP samples during hydration. For this purpose, three α-TCP powders, containing 0, 16 and 71 wt.% of amorphous phase (ATCP), were mixed with either deionized water or a 0.1 M Na 2HPO4 aqueous solution. The crystalline evolution of the paste was assessed quantitatively during the first 48 h of hydration at 23 °C by G-factor quantification. The present investigations demonstrate that ATCP reacted earlier than crystalline α-TCP. The results also suggest the formation of an X-ray amorphous phase during the hydraulic conversion formation of α-TCP into CDHA. © 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

Authors with CRIS profile

Katrin Hurle Lehrstuhl für Mineralogie Jürgen Neubauer Lehrstuhl für Mineralogie Friedlinde Götz-Neunhoeffer Lehrstuhl für Mineralogie

Involved external institutions

RMS Foundation CH Switzerland (CH)

How to cite

APA:

Hurle, K., Neubauer, J., Bohner, M., Döbelin, N., & Götz-Neunhoeffer, F. (2014). Effect of amorphous phases during the hydraulic conversion of alpha-TCP into calcium-deficient hydroxyapatite. Acta Biomaterialia, 10, 3931-3941. https://doi.org/10.1016/j.actbio.2014.03.017

MLA:

Hurle, Katrin, et al. "Effect of amorphous phases during the hydraulic conversion of alpha-TCP into calcium-deficient hydroxyapatite." Acta Biomaterialia 10 (2014): 3931-3941.

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