45S5 Bioglass®-derived scaffolds coated with organic-inorganic hybrids containing graphene

Fabbri P, Valentini L, Hum J, Detsch R, Boccaccini AR (2013)

Publication Type: Journal article

Publication year: 2013

Journal

Materials Science and Engineering C Elsevier

Publisher: Elsevier

Book Volume: 33

Pages Range: 3592-3600

Journal Issue: 7

DOI: 10.1016/j.msec.2013.04.028

Abstract

Highly porous 45S5 Bioglass®-based scaffolds fabricated by a foam replication technique were coated with electrically conductive organic-inorganic hybrid layers containing graphene by a solution method. α,ω- Triethoxysilane terminated poly (ethylene glycol) and tetraethoxysilane were used as the precursors of the organic-inorganic hybrid coatings, that contained 1.5 wt.% of homogeneously dispersed graphene nanoplatelets. The resulting coated scaffolds retained their original high porosity and interconnected pore structure after coating. The presence of graphene did not impair the bioactivity of the scaffolds in simulated body fluid. Initial tests carried out using MG-63 cells demonstrated that both uncoated scaffolds and scaffolds coated with organic/inorganic hybrids containing graphene offered the cultured cells an adequate surface for cell attachment, spreading and expression of extracellular matrix. The results showed that scaffolds coated with graphene are biocompatible and they can support cellular activity. The electrical conductivity introduced by the coating might have the potential to increase tissue growth when cell culture is carried out under an applied electric field. © 2013 Elsevier B.V.

Authors with CRIS profile

Jasmin Hum Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Rainer Detsch Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Università degli Studi di Modena e Reggio Emilia (UNIMORE) IT Italy (IT) Università degli Studi di Perugia IT Italy (IT)

How to cite

APA:

Fabbri, P., Valentini, L., Hum, J., Detsch, R., & Boccaccini, A.R. (2013). 45S5 Bioglass®-derived scaffolds coated with organic-inorganic hybrids containing graphene. Materials Science and Engineering C, 33(7), 3592-3600. https://doi.org/10.1016/j.msec.2013.04.028

MLA:

Fabbri, Paola, et al. "45S5 Bioglass®-derived scaffolds coated with organic-inorganic hybrids containing graphene." Materials Science and Engineering C 33.7 (2013): 3592-3600.

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