Microwave-assisted rapid one-pot synthesis of fused and non-fused indoles and 5-[18F]fluoroindoles from phenylazocarboxylates

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autor(en): Krüll J, Hubert A, Nebel N, Prante O, Heinrich M
Zeitschrift: Chemistry - A European Journal
Jahr der Veröffentlichung: 2017
ISSN: 0947-6539


Abstract


Substituted indoles can be prepared from phenylazo-carboxylates through a rapid one-pot sequence featuring a microwave-assisted Fischer indole synthesis as key step. As the phenylazocarboxylates may beforehand be modified by mild nucleophilic aromatic substitution, including the introduction of [18F]fluoride, the overall strategy offers an attractive new access to 5-[18F]fluoroindoles.



FAU-Autoren / FAU-Herausgeber

Heinrich, Markus Prof. Dr.
Professur für Pharmazeutische Chemie
Krüll, Jasmin
Professur für Pharmazeutische Chemie
Nebel, Natascha
Nuklearmedizinische Klinik
Prante, Olaf Prof. Dr.
Professur für Molekulare Bildgebung und Radiochemie


Zitierweisen

APA:
Krüll, J., Hubert, A., Nebel, N., Prante, O., & Heinrich, M. (2017). Microwave-assisted rapid one-pot synthesis of fused and non-fused indoles and 5-[18F]fluoroindoles from phenylazocarboxylates. Chemistry - A European Journal. https://dx.doi.org/10.1002/chem.201703890

MLA:
Krüll, Jasmin, et al. "Microwave-assisted rapid one-pot synthesis of fused and non-fused indoles and 5-[18F]fluoroindoles from phenylazocarboxylates." Chemistry - A European Journal (2017).

BibTeX: 

Zuletzt aktualisiert 2018-08-10 um 02:16