Microwave-assisted rapid one-pot synthesis of fused and non-fused indoles and 5-[18F]fluoroindoles from phenylazocarboxylates
Beitrag in einer Fachzeitschrift
Details zur Publikation
Autor(en): Krüll J, Hubert A, Nebel N, Prante O, Heinrich M
Zeitschrift: → Chemistry - A European Journal |
Jahr der Veröffentlichung: 2017
ISSN: 0947-6539
Abstract
Substituted indoles can be prepared from phenylazo-carboxylates through a rapid one-pot sequence featuring a microwave-assisted Fischer indole synthesis as key step. As the phenylazocarboxylates may beforehand be modified by mild nucleophilic aromatic substitution, including the introduction of [18F]fluoride, the overall strategy offers an attractive new access to 5-[18F]fluoroindoles.
FAU-Autoren / FAU-Herausgeber
| Heinrich, Markus Prof. Dr. |
| | Professur für Pharmazeutische Chemie |
|
| | | Professur für Pharmazeutische Chemie |
|
| | | Nuklearmedizinische Klinik |
|
| | | Professur für Molekulare Bildgebung und Radiochemie |
|
Zitierweisen
APA: | Krüll, J., Hubert, A., Nebel, N., Prante, O., & Heinrich, M. (2017). Microwave-assisted rapid one-pot synthesis of fused and non-fused indoles and 5-[18F]fluoroindoles from phenylazocarboxylates. Chemistry - A European Journal. https://dx.doi.org/10.1002/chem.201703890 |
MLA: | Krüll, Jasmin, et al. "Microwave-assisted rapid one-pot synthesis of fused and non-fused indoles and 5-[18F]fluoroindoles from phenylazocarboxylates." Chemistry - A European Journal (2017). |