All purpose SOX: The many roles of Sox proteins in gene expression.

Wegner M (2010)


Publication Type: Journal article, Review article

Publication year: 2010

Journal

Publisher: Elsevier

Pages Range: 381-390

Journal Issue: 42

DOI: 10.1016/j.biocel.2009.07.006

Abstract

Sox proteins are found in all metazoans and are active in many developmental processes. Their function as transcription factors is governed by their DNA-binding properties as much as by their interactions with other transcription factors and cofactors, and subject to modulation by posttranslational modifications. Although most Sox proteins predominantly function as transcriptional activators, there is also evidence for transcriptional repression and architectural roles. Further effects involve complex formation of Sox proteins with transcriptionally relevant factors off DNA. Sox proteins may be additionally active on the posttranscriptional level and are therefore remarkably versatile regulators of gene expression. © 2009 Elsevier Ltd. All rights reserved.

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How to cite

APA:

Wegner, M. (2010). All purpose SOX: The many roles of Sox proteins in gene expression. International Journal of Biochemistry & Cell Biology, 42, 381-390. https://doi.org/10.1016/j.biocel.2009.07.006

MLA:

Wegner, Michael. "All purpose SOX: The many roles of Sox proteins in gene expression." International Journal of Biochemistry & Cell Biology 42 (2010): 381-390.

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