Wegner M (2013)
Publication Type: Journal article, Original article
Publication year: 2013
Publisher: Elsevier
Pages Range: 358-363
Journal Issue: 587
DOI: 10.1016/j.febslet.2012.12.017
Sox11 and Sox4 play critical roles in retinal development, during which they display specific and unique expression patterns. The expression of Sox11 and Sox4 is temporally sequential, albeit spatially overlapping in some retinal subtypes. Gain-of-function and loss-of-function analyses suggested that Notch signaling suppresses Sox4 expression in the early developing retina but not during the later period of development. The levels of histone H3-acetylation and H3-lysine 4 tri-methylation at the Sox11 locus declined during development, as did the levels of Sox11. A similar but less marked change was seen for Sox4. For both genes, histone H3-lysine 27 methylation was low during development and increased markedly in the adult. © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
APA:
Wegner, M. (2013). Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinal development. Febs Letters, 587, 358-363. https://doi.org/10.1016/j.febslet.2012.12.017
MLA:
Wegner, Michael. "Expression of Sox4 and Sox11 is regulated by multiple mechanisms during retinal development." Febs Letters 587 (2013): 358-363.
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