Calcium phosphate-based composites as injectable bone substitute materials

Low KL, Tan SH, Zein SHS, Roether JA, Mourino V, Boccaccini AR (2010)

Publication Type: Journal article

Publication year: 2010

Journal

Journal of Biomedical Materials Research Part B-Applied Biomaterials Wiley-Blackwell

Publisher: Wiley-Blackwell

Book Volume: 94B

Pages Range: 273-286

DOI: 10.1002/jbm.b.31619

Abstract

A major weakness of current orthopedic implant materials, for instance sintered hydroxyapatite (HA), is that they exist as a hardened form, requiring the surgeon to fit the surgical site around an implant to the desired shape. This can cause an increase in bone loss, trauma to the surrounding tissue, and longer surgical time. A convenient alternative to harden bone filling materials are injectable bone substitutes (IBS). In this article, recent progress in the development and application of calcium phosphate (CP)-based composites use as IBS is reviewed. CP materials have been used widely for bone replacement because of their similarity to the mineral component of bone. The main limitation of bulk CP materials is their brittle nature and poor mechanical properties. There is significant effort to reinforce or improve the mechanical properties and injectability of calcium phosphate cement (CPC) and this review resumes different alternatives presented in this specialized literature. © 2010 Wiley Periodicals, Inc.

Authors with CRIS profile

Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

University of Science Malaysia (USM) / Universiti Sains Malaysia MY Malaysia (MY) Imperial College London / The Imperial College of Science, Technology and Medicine GB United Kingdom (GB)

How to cite

APA:

Low, K.L., Tan, S.H., Zein, S.H.S., Roether, J.A., Mourino, V., & Boccaccini, A.R. (2010). Calcium phosphate-based composites as injectable bone substitute materials. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 94B, 273-286. https://doi.org/10.1002/jbm.b.31619

MLA:

Low, Kah Ling, et al. "Calcium phosphate-based composites as injectable bone substitute materials." Journal of Biomedical Materials Research Part B-Applied Biomaterials 94B (2010): 273-286.

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