Newly developed Sr-substituted alpha-TCP bone cements
Pina S, Torres PMC, Götz-Neunhoeffer F, Neubauer J, da Fonte Ferreira JM (2010)
Publication Language: English
Publication Type: Journal article
Publication year: 2010
Journal
Publisher: Elsevier
Book Volume: 6
Pages Range: 928-935
Journal Issue: 3
DOI: 10.1016/j.actbio.2009.09.001
Abstract
New bone cements made of Sr-substituted brushite-forming α-tricalcium phosphate (α-TCP) were prepared and characterized in the present work. The quantitative phase analysis and structural refinement of the starting powders and of hardened cements were performed by X-ray powder diffraction and the Rietveld refinement technique. Isothermal calorimetry along with setting time analysis allowed a precise tracing of the setting process of the pastes. The pastes showed exothermic reactions within the first 10-15 min after mixing and further release of heat after about 1 h. An apatitic phase formed upon immersion of the hardened cements in simulated body fluid for 15 and 30 days due to the conversion of brushite into apatite confirming their in vitro mineralization capability. The compressive strength of the wet cement specimens decreased with increasing curing time, being higher in the case of Sr-substituted CPC. The results suggest that the newly developed Sr-substituted brushite-forming α-TCP cements show promise for uses in orthopaedic and trauma surgery such as in filling bone defects. © 2009 Acta Materialia Inc.
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APA:
Pina, S., Torres, P.M.C., Götz-Neunhoeffer, F., Neubauer, J., & da Fonte Ferreira, J.M. (2010). Newly developed Sr-substituted alpha-TCP bone cements. Acta Biomaterialia, 6(3), 928-935. https://dx.doi.org/10.1016/j.actbio.2009.09.001
MLA:
Pina, Sandra, et al. "Newly developed Sr-substituted alpha-TCP bone cements." Acta Biomaterialia 6.3 (2010): 928-935.
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