Newly developed Sr-substituted alpha-TCP bone cements

Journal article

Publication Details

Author(s): Pina S, Torres PMC, Götz-Neunhoeffer F, Neubauer J, da Fonte Ferreira JM
Journal: Acta biomaterialia
Publisher: Elsevier
Publication year: 2010
Volume: 6
Journal issue: 3
Pages range: 928-935
ISSN: 1878-7568
Language: English


New bone cements made of Sr-substituted brushite-forming α-tricalcium phosphate (α-TCP) were prepared and characterized in the present work. The quantitative phase analysis and structural refinement of the starting powders and of hardened cements were performed by X-ray powder diffraction and the Rietveld refinement technique. Isothermal calorimetry along with setting time analysis allowed a precise tracing of the setting process of the pastes. The pastes showed exothermic reactions within the first 10-15 min after mixing and further release of heat after about 1 h. An apatitic phase formed upon immersion of the hardened cements in simulated body fluid for 15 and 30 days due to the conversion of brushite into apatite confirming their in vitro mineralization capability. The compressive strength of the wet cement specimens decreased with increasing curing time, being higher in the case of Sr-substituted CPC. The results suggest that the newly developed Sr-substituted brushite-forming α-TCP cements show promise for uses in orthopaedic and trauma surgery such as in filling bone defects. © 2009 Acta Materialia Inc.

FAU Authors / FAU Editors

Götz-Neunhoeffer, Friedlinde Prof. Dr.
Lehrstuhl für Mineralogie
Neubauer, Jürgen apl. Prof. Dr.
Lehrstuhl für Mineralogie

External institutions with authors

University of Aveiro / Universidade de Aveiro

How to cite

Pina, S., Torres, P.M.C., Götz-Neunhoeffer, F., Neubauer, J., & da Fonte Ferreira, J.M. (2010). Newly developed Sr-substituted alpha-TCP bone cements. Acta biomaterialia, 6(3), 928-935.

Pina, Sandra, et al. "Newly developed Sr-substituted alpha-TCP bone cements." Acta biomaterialia 6.3 (2010): 928-935.


Last updated on 2018-09-08 at 15:08