In Vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements
Pina S, Vieira S, Torres PMC, Götz-Neunhoeffer F, Neubauer J, da Cruz e Silva OAB, da Cruz e Silva EF, da Fonte Ferreira JM (2010)
Publication Type: Journal article
Publication year: 2010
Journal
Publisher: Wiley-Blackwell
Pages Range: 414-420
Journal Issue: 94B (2)
DOI: 10.1002/jbm.b.31669
Abstract
The present study investigated the in vitro performance of brushite-forming Zn- and ZnSr-substituted β-TCP bone cements in terms of wet mechanical strength and biological response. Quantitative phase analysis and structural refinement of the powdered samples were performed by X-ray powder diffraction and Rietveld refinement technique. Initial and final setting times of the cement pastes, measured using Gilmore needles technique, showed that ZnSrCPC sets faster than ZnCPC. The measured values of the wet strength after 48 h of immersion in PBS solution at 37°C showed that ZnSrCPC cements are stronger than ZnCPC cements. Human osteosarcoma-derived MG63 cell line proved the nontoxicity of the cement powders, using the resazurin metabolic assay. © 2010 Wiley Periodicals, Inc.
Authors with CRIS profile
Involved external institutions
University of Aveiro / Universidade de Aveiro
Portugal (PT)
Universidad Autónoma de Nuevo León
Mexico (MX)
Portugal (PT)
Universidad Autónoma de Nuevo León
Mexico (MX)
How to cite
APA:
Pina, S., Vieira, S., Torres, P.M.C., Götz-Neunhoeffer, F., Neubauer, J., da Cruz e Silva, O.A.B.,... da Fonte Ferreira, J.M. (2010). In Vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 94B (2), 414-420. https://doi.org/10.1002/jbm.b.31669
MLA:
Pina, Sandra, et al. "In Vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements." Journal of Biomedical Materials Research Part B-Applied Biomaterials 94B (2) (2010): 414-420.
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