In Vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements

Journal article


Publication Details

Author(s): Pina S, Vieira S, Torres PMC, Götz-Neunhoeffer F, Neubauer J, da Cruz e Silva OAB, da Cruz e Silva EF, da Fonte Ferreira JM
Journal: Journal of Biomedical Materials Research Part B-Applied Biomaterials
Publisher: Wiley-Blackwell
Publication year: 2010
Journal issue: 94B (2)
Pages range: 414-420
ISSN: 1552-4973


Abstract


The present study investigated the in vitro performance of brushite-forming Zn- and ZnSr-substituted β-TCP bone cements in terms of wet mechanical strength and biological response. Quantitative phase analysis and structural refinement of the powdered samples were performed by X-ray powder diffraction and Rietveld refinement technique. Initial and final setting times of the cement pastes, measured using Gilmore needles technique, showed that ZnSrCPC sets faster than ZnCPC. The measured values of the wet strength after 48 h of immersion in PBS solution at 37°C showed that ZnSrCPC cements are stronger than ZnCPC cements. Human osteosarcoma-derived MG63 cell line proved the nontoxicity of the cement powders, using the resazurin metabolic assay. © 2010 Wiley Periodicals, Inc.



FAU Authors / FAU Editors

Götz-Neunhoeffer, Friedlinde Prof. Dr.
Lehrstuhl für Mineralogie
Neubauer, Jürgen apl. Prof. Dr.
Lehrstuhl für Mineralogie


External institutions
Universidad Autónoma de Nuevo León
University of Aveiro


How to cite

APA:
Pina, S., Vieira, S., Torres, P.M.C., Götz-Neunhoeffer, F., Neubauer, J., da Cruz e Silva, O.A.B.,... da Fonte Ferreira, J.M. (2010). In Vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 94B (2), 414-420. https://dx.doi.org/10.1002/jbm.b.31669

MLA:
Pina, Sandra, et al. "In Vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements." Journal of Biomedical Materials Research Part B-Applied Biomaterials 94B (2) (2010): 414-420.

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Last updated on 2018-07-08 at 03:29