Rietveld structure and in vitro analysis on the influence of Magnesium in Biphasic (Hydroxyapatite and beta-Tricalcium phosphate) mixtures

Journal article


Publication Details

Author(s): Kannan S, Götz-Neunhoeffer F, Neubauer J, Rebelo A, Valério P, da Fonte Ferreira JM
Journal: Journal of Biomedical Materials Research Part B-Applied Biomaterials
Publisher: Wiley-Blackwell
Publication year: 2009
Volume: 90
Pages range: 404-411
ISSN: 1552-4973
Language: English


Abstract


The structure of two different Mg-substituted biphasic (HAP and β-TCP) mixtures along with the biphasic mixtures without substituted Mg2+ was investigated using Rietveld refinement technique. The substituted Mg 2+ was found in the β-TCP phase and its influence on the composition has led to an increase in HAP content of Mg-containing biphasic mixtures when compared with the HAP content detected in pure biphasic mixtures. The refined structural parameters of Ca10(PO4) 6(OH)2 and β-Ca3(PO4) 2 confirmed that all the investigated compositions have crystallized in the corresponding hexagonal (space group P63/m) and rhombohedral (space group R3c) structures. The substitution of lower sized magnesium was found preferentially incorporated at the sixfold-coordinated Ca (5) site of β-TCP, which is due to the strong Ca (5)·O interaction among all the five different Ca sites of β-Ca3(PO4)2. The in vitro tests using primary culture of osteoblasts showed that all the tested samples are biocompatible and promising materials for in vivo studies. © 2008 Wiley Periodicals, Inc.



FAU Authors / FAU Editors

Götz-Neunhoeffer, Friedlinde Prof. Dr.
Lehrstuhl für Mineralogie
Neubauer, Jürgen apl. Prof. Dr.
Lehrstuhl für Mineralogie


External institutions
Pondicherry University
Universidade Federal de Minas Gerais (UFMG)
University of Aveiro


How to cite

APA:
Kannan, S., Götz-Neunhoeffer, F., Neubauer, J., Rebelo, A., Valério, P., & da Fonte Ferreira, J.M. (2009). Rietveld structure and in vitro analysis on the influence of Magnesium in Biphasic (Hydroxyapatite and beta-Tricalcium phosphate) mixtures. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 90, 404-411. https://dx.doi.org/10.1002/jbm.b.31299

MLA:
Kannan, Sanjeevi, et al. "Rietveld structure and in vitro analysis on the influence of Magnesium in Biphasic (Hydroxyapatite and beta-Tricalcium phosphate) mixtures." Journal of Biomedical Materials Research Part B-Applied Biomaterials 90 (2009): 404-411.

BibTeX: 

Last updated on 2018-09-08 at 14:53