Rietveld structure and in vitro analysis on the influence of Magnesium in Biphasic (Hydroxyapatite and beta-Tricalcium phosphate) mixtures

Journal article


Publication Details

Author(s): Kannan S, Götz-Neunhoeffer F, Neubauer J, Rebelo A, Valério P, da Fonte Ferreira JM
Journal: Journal of Biomedical Materials Research Part B-Applied Biomaterials
Publisher: Wiley-Blackwell
Publication year: 2009
Volume: 90
Pages range: 404-411
ISSN: 1552-4973
Language: English


Abstract


The structure of two different Mg-substituted biphasic (HAP and β-TCP) mixtures along with the biphasic mixtures without substituted Mg2+ was investigated using Rietveld refinement technique. The substituted Mg 2+ was found in the β-TCP phase and its influence on the composition has led to an increase in HAP content of Mg-containing biphasic mixtures when compared with the HAP content detected in pure biphasic mixtures. The refined structural parameters of Ca10(PO4) 6(OH)2 and β-Ca3(PO4) 2 confirmed that all the investigated compositions have crystallized in the corresponding hexagonal (space group P63/m) and rhombohedral (space group R3c) structures. The substitution of lower sized magnesium was found preferentially incorporated at the sixfold-coordinated Ca (5) site of β-TCP, which is due to the strong Ca (5)·O interaction among all the five different Ca sites of β-Ca3(PO4)2. The in vitro tests using primary culture of osteoblasts showed that all the tested samples are biocompatible and promising materials for in vivo studies. © 2008 Wiley Periodicals, Inc.



FAU Authors / FAU Editors

Götz-Neunhoeffer, Friedlinde Prof. Dr.
Lehrstuhl für Mineralogie
Neubauer, Jürgen apl. Prof. Dr.
Lehrstuhl für Mineralogie


External institutions with authors

Pondicherry University
Universidade Federal de Minas Gerais (UFMG)
University of Aveiro / Universidade de Aveiro


How to cite

APA:
Kannan, S., Götz-Neunhoeffer, F., Neubauer, J., Rebelo, A., Valério, P., & da Fonte Ferreira, J.M. (2009). Rietveld structure and in vitro analysis on the influence of Magnesium in Biphasic (Hydroxyapatite and beta-Tricalcium phosphate) mixtures. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 90, 404-411. https://dx.doi.org/10.1002/jbm.b.31299

MLA:
Kannan, Sanjeevi, et al. "Rietveld structure and in vitro analysis on the influence of Magnesium in Biphasic (Hydroxyapatite and beta-Tricalcium phosphate) mixtures." Journal of Biomedical Materials Research Part B-Applied Biomaterials 90 (2009): 404-411.

BibTeX: 

Last updated on 2018-09-08 at 14:53