Liposomes with conjugates of a calix[4]arene and a Gd-DOTA derivative on the outside surface; An efficient potential contrast agent for MRI

Schuhle DT, Van Rijn P, Laurent S, Vander Elst L, Muller RN, Stuart MCA, Schatz J, Peters JA (2010)

Publication Type: Journal article, Original article

Publication year: 2010

Journal

Chemical Communications Royal Society of Chemistry

Original Authors: Schühle D.T., Van Rijn P., Laurent S., Vander Elst L., Muller R.N., Stuart M.C.A., Schatz J., Peters J.A.

Publisher: Royal Society of Chemistry

Book Volume: 46

Pages Range: 4399-4401

Journal Issue: 24

DOI: 10.1039/c0cc00107d

Abstract

Paramagnetic liposomes used as contrast agents in magnetic resonance imaging (MRI) often suffer from low efficacies because of slow water diffusion through the membrane. We present an approach to overcome this limitation by incorporation of a calix[4]arene based agent that expresses the chelates towards the bulk water. © 2010 The Royal Society of Chemistry.

Authors with CRIS profile

Jürgen Schatz Professur für Organische Chemie

Involved external institutions

Delft University of Technology (TU Delft) NL Netherlands (NL) University of Mons / Université de Mons BE Belgium (BE) University of Groningen / Rijksuniversiteit Groningen NL Netherlands (NL)

How to cite

APA:

Schuhle, D.T., Van Rijn, P., Laurent, S., Vander Elst, L., Muller, R.N., Stuart, M.C.A.,... Peters, J.A. (2010). Liposomes with conjugates of a calix[4]arene and a Gd-DOTA derivative on the outside surface; An efficient potential contrast agent for MRI. Chemical Communications, 46(24), 4399-4401. https://doi.org/10.1039/c0cc00107d

MLA:

Schuhle, Daniel T., et al. "Liposomes with conjugates of a calix[4]arene and a Gd-DOTA derivative on the outside surface; An efficient potential contrast agent for MRI." Chemical Communications 46.24 (2010): 4399-4401.

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