Computation of physiological human vocal fold parameters by mathematical optimization of a biomechanical model.

Beitrag in einer Fachzeitschrift
(Originalarbeit)


Details zur Publikation

Autorinnen und Autoren: Yang A, Stingl M, Berry DA, Lohscheller J, Voigt D, Eysholdt U, Döllinger M
Zeitschrift: Journal of the Acoustical Society of America
Verlag: Acoustical Society of America
Jahr der Veröffentlichung: 2011
Band: 130
Heftnummer: 2
Seitenbereich: 948-964
ISSN: 0001-4966


Abstract


With the use of an endoscopic, high-speed camera, vocal fold dynamics may be observed clinically during phonation. However, observation and subjective judgment alone may be insufficient for clinical diagnosis and documentation of improved vocal function, especially when the laryngeal disease lacks any clear morphological presentation. In this study, biomechanical parameters of the vocal folds are computed by adjusting the corresponding parameters of a three-dimensional model until the dynamics of both systems are similar. First, a mathematical optimization method is presented. Next, model parameters (such as pressure, tension and masses) are adjusted to reproduce vocal fold dynamics, and the deduced parameters are physiologically interpreted. Various combinations of global and local optimization techniques are attempted. Evaluation of the optimization procedure is performed using 50 synthetically generated data sets. The results show sufficient reliability, including 0.07 normalized error, 96% correlation, and 91% accuracy. The technique is also demonstrated on data from human hemilarynx experiments, in which a low normalized error (0.16) and high correlation (84%) values were achieved. In the future, this technique may be applied to clinical high-speed images, yielding objective measures with which to document improved vocal function of patients with voice disorders.



FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Döllinger, Michael Prof. Dr.
Professur für Computational Medicine (DFG-Forschungsprofessur)
Lohscheller, Jörg PD Dr.
Medizinische Fakultät
Stingl, Michael Prof. Dr.
Professur für Angewandte Mathematik (Kontinuierliche Optimierung)
Yang, Anxiong
Graduiertenzentrum der FAU


Einrichtungen weiterer Autorinnen und Autoren

Max Planck Institute for Evolutionary Anthropology / Max-Planck-Institut für evolutionäre Anthropologie
University of California Los Angeles (UCLA)


Zitierweisen

APA:
Yang, A., Stingl, M., Berry, D.A., Lohscheller, J., Voigt, D., Eysholdt, U., & Döllinger, M. (2011). Computation of physiological human vocal fold parameters by mathematical optimization of a biomechanical model. Journal of the Acoustical Society of America, 130(2), 948-964. https://dx.doi.org/10.1121/1.3605551

MLA:
Yang, Anxiong, et al. "Computation of physiological human vocal fold parameters by mathematical optimization of a biomechanical model." Journal of the Acoustical Society of America 130.2 (2011): 948-964.

BibTeX: 

Zuletzt aktualisiert 2018-11-08 um 02:16