Evaluation of competing process concepts for the production of pure enantiomers

Beitrag in einer Fachzeitschrift
(Originalarbeit)


Details zur Publikation

Autorinnen und Autoren: Kaspereit M, Swernath S, Kienle A
Zeitschrift: Organic Process Research & Development
Verlag: American Chemical Society
Jahr der Veröffentlichung: 2012
Band: 16
Heftnummer: 2
Seitenbereich: 353-363
ISSN: 1083-6160
Sprache: Englisch


Abstract


Various promising concepts exist for improving the performance of productions of pure enantiomers. An efficient approach is developed for the systematic conceptual design of such processes. The proposed three-step procedure aids a fast selection of the optimal process configuration out of many possible candidates and leads to an optimally designed process. The approach is applied in a case study for an industrially relevant compound, considering different process concepts based on simulated moving bed chromatography, enantioselective crystallization, and racemization. It is demonstrated that mixed-integer nonlinear programming is capable of predicting simultaneously the optimal process configuration and optimal design parameters. © 2011 American Chemical Society.



FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Kaspereit, Malte Prof. Dr.-Ing.
Professur für Thermische Verfahrenstechnik


Zitierweisen

APA:
Kaspereit, M., Swernath, S., & Kienle, A. (2012). Evaluation of competing process concepts for the production of pure enantiomers. Organic Process Research & Development, 16(2), 353-363. https://dx.doi.org/10.1021/op200285v

MLA:
Kaspereit, Malte, Subramanian Swernath, and Achim Kienle. "Evaluation of competing process concepts for the production of pure enantiomers." Organic Process Research & Development 16.2 (2012): 353-363.

BibTeX: 

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