Peptide-size-dependent active transport in the proteasome

Zaikin A, Pöschel T (2005)

Publication Language: English

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2005

Journal

EPL - Europhysics Letters Institute of Physics: EPL

Publisher: Institute of Physics: EPL

Book Volume: 69

Pages Range: 725-731

Journal Issue: 5

DOI: 10.1209/epl/i2004-10426-8

Abstract

We investigate the transport of proteins inside the proteasome and propose an active-transport mechanism based on a spatially asymmetric interaction potential of peptide chains. The transport is driven by fluctuations which are always present in such systems. We compute the peptide-size-dependent transport rate which is essential for the functioning of the proteasome. In agreement with recent experiments, varying temperature changes the transport mechanism qualitatively. © EDP Sciences.

Authors with CRIS profile

Thorsten Pöschel Lehrstuhl für Multiscale Simulation of Particulate Systems

Involved external institutions

University of Exeter GB United Kingdom (GB)

How to cite

APA:

Zaikin, A., & Pöschel, T. (2005). Peptide-size-dependent active transport in the proteasome. EPL - Europhysics Letters, 69(5), 725-731. https://dx.doi.org/10.1209/epl/i2004-10426-8

MLA:

Zaikin, A., and Thorsten Pöschel. "Peptide-size-dependent active transport in the proteasome." EPL - Europhysics Letters 69.5 (2005): 725-731.

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