Principles of the prolactin/vasoinhibin axis

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autorinnen und Autoren: Triebel J, Bertsch T, Bollheimer C, Rios-Barrera D, Pearce CF, Huefner M, Martnez De La Escalera G, Clapp C
Zeitschrift: American Journal of Physiology-Regulatory Integrative and Comparative Physiology
Jahr der Veröffentlichung: 2015
Band: 309
Heftnummer: 10
Seitenbereich: R1193-203
ISSN: 0363-6119


Abstract

The hormonal family of vasoinhibins, which derive from the anterior pituitary hormone prolactin, are known for their inhibiting effects on blood vessel growth, vasopermeability, and vasodilation. As pleiotropic hormones, vasoinhibins act in multiple target organs and tissues. The generation, secretion, and regulation of vasoinhibins are embedded into the organizational principle of an axis, which integrates the hypothalamus, the pituitary, and the target tissue microenvironment. This axis is designated as the prolactin/vasoinhibin axis. Disturbances of the prolactin/vasoinhibin axis are associated with the pathogenesis of retinal and cardiac diseases and with diseases occurring during pregnancy. New phylogenetical, physiological, and clinical implications are discussed.


FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Bollheimer, Cornelius Prof. Dr.
Professur für Innere Medizin - Geriatrie


Einrichtungen weiterer Autorinnen und Autoren

Centura Health
European Molecular Biology Laboratory (EMBL)
MVZ Endokrinologikum
National Autonomous University of Mexico / Universidad Nacional Autónoma de México (UNAM)
Paracelsus Medizinische Privatuniversität


Zitierweisen

APA:
Triebel, J., Bertsch, T., Bollheimer, C., Rios-Barrera, D., Pearce, C.F., Huefner, M.,... Clapp, C. (2015). Principles of the prolactin/vasoinhibin axis. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 309(10), R1193-203. https://dx.doi.org/10.1152/ajpregu.00256.2015

MLA:
Triebel, Jakob, et al. "Principles of the prolactin/vasoinhibin axis." American Journal of Physiology-Regulatory Integrative and Comparative Physiology 309.10 (2015): R1193-203.

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Zuletzt aktualisiert 2018-05-10 um 07:22