Schambony A (1998)
Publication Language: English
Publication Type: Journal article, Original article
Subtype: other
Publication year: 1998
Book Volume: 1387
Pages Range: 206-216
Journal Issue: 1-2
DOI: 10.1016/S0167-4838(98)00122-8
Although originally described in the male rodent genital tract, cysteine-rich secretory proteins (CRISPs) are expressed in a variety of mammalian tissue and cell types. The proteins of the male genital tract have been observed associated to spermatozoa and are believed to play a role in mammalian fertilization. Here we describe the identification and primary structure of the first equine member of the CRISP family. Equine CRISP-3 is transcribed and expressed in the stallion salivary gland, in the ampulla and the seminal vesicle. It displays all 16 conserved cysteine residues and shows 82% homology to human and 78% to guinea pig CRISP-2 (AA1, TPX 1) and 77% to human CRISP-3. In contrast to other mammalia, in the horse CRISP-3 is synthesized in great amounts in the accessory sexual glands, ampulla and seminal vesicle, thus allowing the isolation of equine CRISP-3 in amounts suitable for biochemical, physiological and structural studies from stallion seminal plasma.
APA:
Schambony, A. (1998). Equine CRISP-3: primary structure and expression in the male genital tract. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1387(1-2), 206-216. https://dx.doi.org/10.1016/S0167-4838(98)00122-8
MLA:
Schambony, Alexandra. "Equine CRISP-3: primary structure and expression in the male genital tract." Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 1387.1-2 (1998): 206-216.
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