45S5 bioactive glass-based scaffolds coated with cellulose nanowhiskers for bone tissue engineering

Li W, Garmendia N, De Larraya UP, Ding Y, Detsch R, Gruenewald A, Roether J, Schubert DW, Boccaccini AR (2014)

Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2014

Journal

Publisher: Royal Society of Chemistry

Book Volume: 4

Pages Range: 56156-56164

Journal Issue: 99

DOI: 10.1039/c4ra07740g

Abstract

Highly porous 45S5 bioactive glass-based scaffolds prepared by foam replication method were coated with cellulose nanowhiskers by dip coating method. The obtained cellulose nanowhisker-coated scaffolds retained the high porosity and interconnected pore structure. The cellulose coating improved the mechanical properties of the scaffolds and did not hinder their bioactivity in simulated body fluid. In vitro biocompatibility assessment was carried out by qualitative evaluation of the morphology of osteoblast-like cells (MG-63) seeded onto the scaffolds. The cells were shown to attach and spread on both uncoated scaffolds and cellulose nanowhisker-coated scaffolds, thus cellulose nanowhisker coating seems to have no negative influence on the behavior of MG-63 cells. The obtained bioactive and biocompatible composite scaffolds represent promising candidates for bone tissue engineering applications.

Authors with CRIS profile

Involved external institutions

Centro Multidisciplinar de Tecnologias para la Industria (CEMITEC) Spain (ES)

How to cite

APA:

Li, W., Garmendia, N., De Larraya, U.P., Ding, Y., Detsch, R., Gruenewald, A.,... Boccaccini, A.R. (2014). 45S5 bioactive glass-based scaffolds coated with cellulose nanowhiskers for bone tissue engineering. RSC Advances, 4(99), 56156-56164. https://doi.org/10.1039/c4ra07740g

MLA:

Li, Wei, et al. "45S5 bioactive glass-based scaffolds coated with cellulose nanowhiskers for bone tissue engineering." RSC Advances 4.99 (2014): 56156-56164.

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