Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autor(en): Stadler AM, Embs JP, Digel I, Artmann G, Unruh T, Büldt G, Zaccai G
Zeitschrift: Journal of the American Chemical Society
Verlag: AMER CHEMICAL SOC
Jahr der Veröffentlichung: 2008
Band: 130
Heftnummer: 50
Seitenbereich: 16852-+
ISSN: 0002-7863


Abstract


The dynamics of water in human red blood cells was measured with quasielastic incoherent neutron scattering in the temperature range between 290 and 320 K. Neutron spectrometers with time resolutions of 40, 13, and 7 ps were combined to cover time scales of bulk water dynamics to reduced mobility interfacial water motions. A major fraction of similar to 90% of cell water is characterized by a translational diffusion coefficient similar to bulk water. A minor fraction of similar to 10% of cellular water exhibits reduced dynamics. This slow water fraction was attributed to dynamically bound water on the surface of hemoglobin which accounts for approximately half of the hydration layer.



FAU-Autoren / FAU-Herausgeber

Unruh, Tobias Prof. Dr.
Professur für Nanomaterialcharakterisierung (Streumethoden)


Autor(en) der externen Einrichtung(en)
Fachhochschule Aachen
Forschungszentrum Jülich GmbH (FZJ)
Institute Laue-Langevin (ILL)
Paul Scherrer Institute (PSI)


Zitierweisen

APA:
Stadler, A.M., Embs, J.P., Digel, I., Artmann, G., Unruh, T., Büldt, G., & Zaccai, G. (2008). Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells. Journal of the American Chemical Society, 130(50), 16852-+. https://dx.doi.org/10.1021/ja807691j

MLA:
Stadler, Andreas M., et al. "Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells." Journal of the American Chemical Society 130.50 (2008): 16852-+.

BibTeX: 

Zuletzt aktualisiert 2018-06-08 um 20:11