Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells
Stadler AM, Embs JP, Digel I, Artmann G, Unruh T, Büldt G, Zaccai G (2008)
Publication Status: Published
Publication Type: Journal article
Publication year: 2008
Journal
Publisher: AMER CHEMICAL SOC
Book Volume: 130
Pages Range: 16852-16853
Journal Issue: 50
DOI: 10.1021/ja807691j
Abstract
The dynamics of water in human red blood cells was measured with quasielastic incoherent neutron scattering in the temperature range between 290 and 320 K. Neutron spectrometers with time resolutions of 40, 13, and 7 ps were combined to cover time scales of bulk water dynamics to reduced mobility interfacial water motions. A major fraction of similar to 90% of cell water is characterized by a translational diffusion coefficient similar to bulk water. A minor fraction of similar to 10% of cellular water exhibits reduced dynamics. This slow water fraction was attributed to dynamically bound water on the surface of hemoglobin which accounts for approximately half of the hydration layer.
Authors with CRIS profile
Involved external institutions
Paul Scherrer Institute (PSI)
Switzerland (CH)
Fachhochschule Aachen - Aachen University of Applied Sciences
Germany (DE)
Forschungszentrum Jülich / Research Centre Jülich (FZJ)
Germany (DE)
Institute Laue-Langevin (ILL)
France (FR)
Switzerland (CH)
Fachhochschule Aachen - Aachen University of Applied Sciences
Germany (DE)
Forschungszentrum Jülich / Research Centre Jülich (FZJ)
Germany (DE)
Institute Laue-Langevin (ILL)
France (FR)
How to cite
APA:
Stadler, A.M., Embs, J.P., Digel, I., Artmann, G., Unruh, T., Büldt, G., & Zaccai, G. (2008). Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells. Journal of the American Chemical Society, 130(50), 16852-16853. https://dx.doi.org/10.1021/ja807691j
MLA:
Stadler, Andreas M., et al. "Cytoplasmic Water and Hydration Layer Dynamics in Human Red Blood Cells." Journal of the American Chemical Society 130.50 (2008): 16852-16853.
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