Hoffmann I, Blumenröder B, Onodi S, Dommer S, Schatz J (2015)
Publication Status: Published
Publication Type: Journal article, Original article
Publication year: 2015
Publisher: Royal Society of Chemistry
Book Volume: 17
Pages Range: 3844-3857
Journal Issue: 7
DOI: 10.1039/c5gc00794a
We report a simple and efficient procedure for the ligand-free as well as ligand-assisted Suzuki reaction in both pure water and aqueous media. The cross-coupling reactions proceed successfully using phenylboronic acid or potassium phenyltrifluoroborate as a nucleophilic coupling partner. The method can be effectively applied to both activated and deactivated aryl halides yielding quantitative conversions. The catalytic activity of couplings performed in pure water increases when utilizing supramolecular additives, but decreases under standard phase-transfer conditions. Finally, the palladium loading is reducible from 3.0 mol% to 0.4 mol% without any loss of conversion.
APA:
Hoffmann, I., Blumenröder, B., Onodi, S., Dommer, S., & Schatz, J. (2015). Suzuki cross-coupling in aqueous media. Green Chemistry, 17(7), 3844-3857. https://dx.doi.org/10.1039/c5gc00794a
MLA:
Hoffmann, Ina, et al. "Suzuki cross-coupling in aqueous media." Green Chemistry 17.7 (2015): 3844-3857.
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