Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions

Schmiele M, Busch S, Morhenn H, Schindler T, Schmutzler T, Schweins R, Lindner P, Boesecke P, Westermann M, Steiniger F, Funari SS, Unruh T (2016)


Publication Status: Published

Publication Type: Journal article, Original article

Publication year: 2016

Journal

Publisher: American Chemical Society

Book Volume: 120

Pages Range: 5505-5512

Journal Issue: 24

DOI: 10.1021/acs.jpcb.6b02519

Abstract

The structure of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)-stabilized colloidal tetracosane emulsions was investigated by photon correlation spectroscopy and small-angle X-ray and neutron scattering, using emulsions with different neutron scattering contrasts. Special emphasis was placed on the structure of the DMPC stabilizer layer covering the emulsion droplets. A monolayer, structurally similar to a half DMPC bilayer, with a thickness of 16 å is found. Thereby, the phosphocholine headgroups arrange flat at the oil-water interface. A deep penetration of the tetracosane oil into the stabilizer layer can be ruled out.

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APA:

Schmiele, M., Busch, S., Morhenn, H., Schindler, T., Schmutzler, T., Schweins, R.,... Unruh, T. (2016). Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions. Journal of Physical Chemistry B, 120(24), 5505-5512. https://dx.doi.org/10.1021/acs.jpcb.6b02519

MLA:

Schmiele, Martin, et al. "Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions." Journal of Physical Chemistry B 120.24 (2016): 5505-5512.

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