Frasch M (2008)
Publication Status: Published
Publication Type: Journal article, Review article
Publication year: 2008
Publisher: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Book Volume: 22
Pages Range: 1572-1576
Journal Issue: 12
DOI: 10.1101/gad.1690608
The first microRNAs were identified in Caenorhabditis elegans based on their functions in the temporal regulation of stage-specific cell fate decisions. Until now, it was not known whether the so-called heterochronic genes that encode miRNAs are also involved in controlling developmental transitions in other organisms. New findings by Sokol et al. (this issue of Genes & Development, pp. 1591-1596) demonstrate that the Drosophila counterpart of a heterochronic miRNA gene from C. elegans, let-7, does indeed play a role in promoting stage-specific developmental events in neuromuscular tissues during the transition from larval to adult stages, thus pointing to a more widespread utilization of miRNAs in temporal regulation of animal development.
APA:
Frasch, M. (2008). A matter of timing: microRNA-controlled temporal identities in worms and flies. Genes & Development, 22(12), 1572-1576. https://dx.doi.org/10.1101/gad.1690608
MLA:
Frasch, Manfred. "A matter of timing: microRNA-controlled temporal identities in worms and flies." Genes & Development 22.12 (2008): 1572-1576.
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