Regulatory and Cellular Functions of Plant RhoGAPs and RhoGDIs

Article in Edited Volumes
(Book chapter)


Publication Details

Author(s): Kost B
Editor(s): Yalovsky, Shaul, Baluška, František, Jones, Alan (Eds.)
Title edited volumes: Integrated G Proteins Signaling in Plants
Publisher: Springer-Verlag Berlin Heidelberg
Publication year: 2010
Title of series: Signaling and Communication in Plants
Pages range: 27-48
ISBN: 978-3-642-03523-4
ISSN: 1867-9048


Abstract


Rho GTPases play central roles in the regulation of essential cellular


processes, such as directional expansion, motility, and division. RhoGEFs (Guanine


Nucleotide Exchange Factors) have key functions in the stimulus-induced spatiotemporal


control of Rho GTPase activity. RhoGAPs (GTPase activating proteins)


and RhoGDIs (Guanine nucleotide dissociation inhibitors) have long been seen as


less important regulators of Rho GTPase activity, with functions largely restricted


to the constitutive attenuation of Rho signaling. Extended families of diverse


RhoGAPs, as well as small families of structurally similar RhoGDIs, have been


identified in yeast, animals, and plants. Recent research has established that members


of these protein families play much more important and complex roles than


previously anticipated in the regulation of Rho GTPase activity and cellular processes.


Non-plant RhoGAPs and RhoGDIs were shown to be tightly regulated by


upstream signaling, and the same is likely to be true for their plant homologs as


well. The recent functional characterization of plant RhoGAPs and RhoGDIs has


allowed exciting and universally important insights into the molecular mechanisms


underlying the control of Rho GTPase activity by these proteins.



External institutions
Swedish University of Agricultural Sciences / Sveriges Lantbruksuniversitet (SLU)


How to cite

APA:
Kost, B. (2010). Regulatory and Cellular Functions of Plant RhoGAPs and RhoGDIs. In Yalovsky, Shaul, Baluška, František, Jones, Alan (Eds.) (Eds.), Integrated G Proteins Signaling in Plants (pp. 27-48). Springer-Verlag Berlin Heidelberg.

MLA:
Kost, Benedikt. "Regulatory and Cellular Functions of Plant RhoGAPs and RhoGDIs." Integrated G Proteins Signaling in Plants Ed. Yalovsky, Shaul, Baluška, František, Jones, Alan (Eds.), Springer-Verlag Berlin Heidelberg, 2010. 27-48.

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Last updated on 2018-11-08 at 01:24