Motor output complexity in Parkinson's disease during quiet standing and walking: Analysis of short-term correlations using the entropic half-life.

Beitrag in einer Fachzeitschrift


Details zur Publikation

Autor(en): Pasluosta CF, Hannink J, Gaßner H, von Tscharner V, Winkler J, Klucken J, Eskofier B
Zeitschrift: Human movement science
Jahr der Veröffentlichung: 2018
Band: 58
Seitenbereich: 185-194
ISSN: 1872-7646


Abstract


Parkinson's disease (PD) is associated with alterations in motor outputs such as center of pressure (CoP) adjustments during quiet standing and foot kinematics during walking. Previous research suggests that the complexity of motor outputs reflects the number of control processes stabilizing a specific movement, providing a measure that is linked to the neurological control of the movement. The Entropic Half Life (EnHL) represents a new method for assessing motor output complexity. We hypothesized that there will be a lack of neuromuscular control pathways for PD patients, resulting in a decrease in motor output complexity. We computed the EnHL of CoP adjustments during quiet standing and foot kinematics during walking of 70 PD patients and 33 age-matched controls. Patients with PD showed longer EnHL values compared to controls, suggesting a tighter motor control. Excluding vision led to a decrease of EnHL of CoP in both groups. EnHL was correlated with spatio-temporal gait parameters. We compared EnHL with the pull test and the timed up-and-go test. No significant differences were present in the pull test, yet motor output complexity was correlated with the timed up-and-go test. The results suggest a reduced complexity in motor outputs of PD patients affecting distinct motor functions.



FAU-Autoren / FAU-Herausgeber

Eskofier, Björn Prof. Dr.
Lehrstuhl für Informatik 14 (Maschinelles Lernen und Datenanalytik)
Molekular-Neurologische Abteilung in der Neurologischen Klinik
Gaßner, Heiko Dr. phil.
Hannink, Julius
Lehrstuhl für Informatik 14 (Maschinelles Lernen und Datenanalytik)
Klucken, Jochen Prof. Dr.
Molekular-Neurologische Abteilung in der Neurologischen Klinik
Winkler, Jürgen Prof. Dr.
Professur für Molekulare Neurologie


Autor(en) der externen Einrichtung(en)
Albert-Ludwigs-Universität Freiburg


Zitierweisen

APA:
Pasluosta, C.F., Hannink, J., Gaßner, H., von Tscharner, V., Winkler, J., Klucken, J., & Eskofier, B. (2018). Motor output complexity in Parkinson's disease during quiet standing and walking: Analysis of short-term correlations using the entropic half-life. Human movement science, 58, 185-194. https://dx.doi.org/10.1016/j.humov.2018.02.005

MLA:
Pasluosta, C. F., et al. "Motor output complexity in Parkinson's disease during quiet standing and walking: Analysis of short-term correlations using the entropic half-life." Human movement science 58 (2018): 185-194.

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Zuletzt aktualisiert 2019-01-01 um 23:10