Clinical management of patients receiving cell-based immunoregulatory therapy.

Beitrag in einer Fachzeitschrift
(Review-Artikel)


Details zur Publikation

Autor(en): Walter L
Zeitschrift: Transfusion
Jahr der Veröffentlichung: 2014
Band: 54
Heftnummer: 9
Seitenbereich: 2336-43
ISSN: 1537-2995


Abstract


Administering immunoregulatory cells as medicinal agents is a revolutionary approach to the treatment of immunologically mediated diseases. Isolating, propagating, and modifying cells before applying them to patients allows complementation of specific cellular functions, which opens astonishing new possibilities for gain-of-function antigen-specific treatments in autoimmunity, chronic inflammatory disorders, and transplantation. This critical review presents a systematic assessment of the potential clinical risks posed by cell-based immunotherapy, focusing on treatment of renal transplant recipients with regulatory macrophages as a concrete example.



FAU-Autoren / FAU-Herausgeber

Walter, Lisa Dr.
Lehrstuhl für Informatik 14 (Maschinelles Lernen und Datenanalytik)

Zuletzt aktualisiert 2018-11-08 um 02:28