Hydration mechanism of partially amorphized β-tricalcium phosphate

Beitrag in einer Fachzeitschrift

Details zur Publikation

Autorinnen und Autoren: Hurle K, Neubauer J, Götz-Neunhoeffer F
Zeitschrift: Acta Biomaterialia
Verlag: Elsevier Ltd
Jahr der Veröffentlichung: 2017
Band: 54
Seitenbereich: 429-440
ISSN: 1742-7061
Sprache: Englisch


Calcium phosphate cements (CPCs) are applied as bone cements due to their excellent biocompatibility. In the present study, the quantitative phase content development during hydration of partially amorphized β-tricalcium phosphate (β-TCP) within the first 24 h was investigated by in-situ X-ray diffraction (XRD) combined with the G-factor method, an external standard method. The quantity of amorphous phase (ATCP) in the powders was determined by the G-factor method.

The hydration model established for partially amorphized β-TCP indicates that ATCP reacted first, followed by the hydration of a small fraction of crystalline β-TCP starting after some h. Consequently, hydration resulted in biphasic samples composed of calcium deficient hydroxyapatite (CDHA) and crystalline β-TCP. The ratio wt%(CDHA)/wt%(β-TCP) after 24 h hydration was adjustable by the initial ATCP content. The crystallinity of CDHA was nearly independent of the ATCP content. Since the biological degradability of CDHA and β-TCP differ, the degradation performance of the set cements is expected to be adjustable by varying the ATCP content. The present study provided a basic understanding of the hydration mechanism of partially amorphized β-TCP, which is the prerequisite for the development of applicable CPC formulations.

FAU-Autorinnen und Autoren / FAU-Herausgeberinnen und Herausgeber

Götz-Neunhoeffer, Friedlinde Prof. Dr.
Lehrstuhl für Mineralogie
Hurle, Katrin Dr.
Lehrstuhl für Mineralogie
Neubauer, Jürgen apl. Prof. Dr.
Lehrstuhl für Mineralogie


Neue Materialien und Licht-Materie-Wechselwirkung
Forschungsschwerpunkt einer Fakultät: Naturwissenschaftliche Fakultät
Neue Materialien und Prozesse
Forschungsschwerpunkt einer Fakultät: Technische Fakultät


Hurle, K., Neubauer, J., & Götz-Neunhoeffer, F. (2017). Hydration mechanism of partially amorphized β-tricalcium phosphate. Acta Biomaterialia, 54, 429-440. https://dx.doi.org/10.1016/j.actbio.2017.03.013

Hurle, Katrin, Jürgen Neubauer, and Friedlinde Götz-Neunhoeffer. "Hydration mechanism of partially amorphized β-tricalcium phosphate." Acta Biomaterialia 54 (2017): 429-440.


Zuletzt aktualisiert 2019-30-08 um 12:38