P103: Determining the role of phosphorylation in nuclear envelope MTOC formation
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.04.2022
End date : 31.03.2023
Project details
Scientific Abstract
Phosphorylation is a well-known regulatory mechanism of MTOC activity at the centrosome. In contrast, it is unknown, whether non-centrosomal MTOCs are also regulated by phosphorylation. We aim at determining how phosphorylation is utilized to regulate MTOC formation at the nuclear envelope. For this, we will examine a potential role of candidate enzymes derived from preliminary data as well as utilize screening approaches to identify novel regulators of nuclear envelope MTOC formation.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Nephropathology
Medizinische Fakultät
