P107: Neurosteroids in the hippocampus and their effects on calcium homeostasis in both sexes.
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.03.2022
End date : 30.11.2022
Project details
Scientific Abstract
Learning and memory formation are influenced in a sex-specific manner by neurosteroids, such as 17beta-estradiol and dehydrotestosterone. However, the structural mechanisms of how de novo synthesis of local neurosteroids in hippocampal neurons and their regulation by gonadotropin releasing hormone (GnRH) lead to the formation and degradation of spine synapses are still poorly understood. The focus of this work is to investigate its influence on calcium homeostasis in both sexes.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Professur für Neuromorphologie
Medizinische Fakultät
