P076: MRI based quantification of myelin for the early differential diagnosis of Multiple System Atrophy

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.06.2021

End date : 31.05.2022

Extension date: 30.11.2023

Project details

Scientific Abstract

Diagnosis of the rare neurodegenerative disease multisystem atrophy (MSA) is hampered by a lack of biomarkers. We could show that in an MSA mouse model, a myelin deficit can be visualized by quant. susceptibility mapping (QSM)on MRI. Our preliminary clinical data show similar results. The aim is now to comprehensively assess QSM imaging as a biomarker for the differential diagnosis of neurodegenerative diseases.

Involved:

Franz Marxreiter Project Leader Manuel Schmidt Project Member Frederik Bernd Laun Project Member

Contributing FAU Organisations:

Professur für quantitative MR-Bildgebung Interdisziplinäres Zentrum für Klinische Forschung (IZKF) Department of Neuroradiology Department of Molecular Neurology Medizinische Fakultät

Research Areas

Microscope SVG ELAN-Pilot Projects Field of Research