A comparative study of cystoid macula edema following glaucoma drainage device surgery versus trabeculectomy
Gietzelt C, Koenig L, Adler W, Schaub F, Heindl LM, Cursiefen C, Dietlein TS, Enders P (2024)
Publication Type: Journal article
Publication year: 2024
Journal
Book Volume: 44
Article Number: 150
Journal Issue: 1
DOI: 10.1007/s10792-024-03068-y
Abstract
Purpose: To assess and compare the risk for development of cystoid macula edema (CME) after glaucoma drainage device (GDD) implantation versus conventional trabeculectomy with mitomycin (trab) for glaucoma. Methods: Retrospective review of consecutive patients receiving trab or GDD implantation between 2016 and 2018. Inclusion criteria were availability of pre- and postoperative spectral domain optical coherence tomography (SD-OCT) of the macula. SD-OCT images were evaluated for presence of CME qualitatively, central subfield thickness (CST) and macular volume (MV). Results: 73 eyes could be included, 42 received trab and 31 GDD surgery. Eyes receiving trab on average had 0.8 ± 0.8 previous intraocular operations, while eyes with GDD implantation had 3.1 ± 1.9 (p < 0.001). Occurrence of postoperative CME was significantly more frequent after GDD implantation (6 out of 31 (19.4%)) than after trab (2 out of 42 eyes = 4.8%), (p = 0.049). Mean preoperative CST as well as MV was comparable in both groups (CST before trab: 282.7 ± 23.0 µm, CST before GDD 284.2 ± 27.3 µm, p = 0.287; MV before trab: 7.8 ± 1.1 mm3, MV before GDD: 8.0 ± 0.8mm3, p = 0.305). Mean postoperative CST and MV were significantly higher after GDD (CST 338.5 ± 129.3 µm, MV 8.8 ± 2.6 mm3) than after trabeculectomy (CST 290.6 ± 60.2 µm, p = 0.038; MV 7.8 ± 1.2mm3, p = 0.039). Conclusions: In real-life conditions, GDD surgery seems to be associated with a higher risk to develop CME when compared to conventional trabeculectomy. This information may be helpful for glaucoma surgeons to advise the patients on postoperative risks of surgery.
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APA:
Gietzelt, C., Koenig, L., Adler, W., Schaub, F., Heindl, L.M., Cursiefen, C.,... Enders, P. (2024). A comparative study of cystoid macula edema following glaucoma drainage device surgery versus trabeculectomy. International Ophthalmology, 44(1). https://doi.org/10.1007/s10792-024-03068-y
MLA:
Gietzelt, Caroline, et al. "A comparative study of cystoid macula edema following glaucoma drainage device surgery versus trabeculectomy." International Ophthalmology 44.1 (2024).
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