Ronicke M, Berking C, Erfurt-Berge C (2024)
Publication Type: Journal article
Publication year: 2024
DOI: 10.1111/ddg.15276
The term occluding vasculopathies covers a large number of different conditions. These often manifest as skin ulcers. Occluding vasculopathies should be considered in the differential diagnosis of leg ulcers. The term “occlusive vasculopathies” encompasses pathophysiologically related entities that share structural or thrombotic obliteration of small cutaneous vessels. In this article, we will focus on livedoid vasculopathy with and without antiphospholipid syndrome and calciphylaxis with differentiation from hypertonic leg ulcer as the most relevant differential diagnoses of leg ulcer. The term also includes vascular occlusion, for example due to oxalate or cholesterol embolism, and septic vasculopathy. This often leads to acral ulceration and is therefore not a differential diagnosis with classic leg ulcers. It will not be discussed in this article. Occlusive vasculopathy may be suspected in the presence of the typical livedo racemosa or (non-inflammatory) retiform purpura as a sign of reduced cutaneous perfusion in the wound area. Inflammatory dermatoses, especially vasculitides, must be differentiated. This is achieved by histopathological evaluation of a tissue sample of sufficient size and depth taken at the appropriate time. In addition, specific laboratory parameters, particularly coagulation parameters, can support the diagnosis.
APA:
Ronicke, M., Berking, C., & Erfurt-Berge, C. (2024). Occlusive cutaneous vasculopathies as cause of chronic ulcers. Journal der Deutschen Dermatologischen Gesellschaft. https://doi.org/10.1111/ddg.15276
MLA:
Ronicke, Moritz, Carola Berking, and Cornelia Erfurt-Berge. "Occlusive cutaneous vasculopathies as cause of chronic ulcers." Journal der Deutschen Dermatologischen Gesellschaft (2024).
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