Survival after cryptococcosis in Germany: A retrospective multicenter cohort study of patients diagnosed between 2004 and 2021

Kessel J, Rossaert AC, Lingscheid T, Grothe J, Harrer T, Wyen C, Tominski D, Bollinger T, Kehr AK, Kalbitz S, Hoffmann C, Cornely O, Koppe U, Stephan C, Rickerts V (2024)

Publication Type: Journal article

Publication year: 2024

Journal

International Journal of Medical Microbiology Elsevier

Book Volume: 314

Article Number: 151614

DOI: 10.1016/j.ijmm.2024.151614

Abstract

Cryptococcosis is the most prevalent fungal infection of the central nervous system worldwide. We performed a retrospective multicenter cohort study to gain insights into the epidemiology of cryptococcosis in Germany. We describe the use of diagnostic tests, clinical management and patient outcome. We included 64 patients with underlying HIV infection (55%) or other predispositions. Molecular typing by MLST documented 20 individual sequence types among 42 typed isolates. A fatal outcome was documented in 14% of patients in the first two months after diagnosis.

Authors with CRIS profile

Thomas Harrer Professur für Innere Medizin mit dem Schwerpunkt Immundefizienz

Involved external institutions

Universitätsklinikum Frankfurt am Main (KGU) DE Germany (DE) ICH Hamburg - Stendal GbR DE Germany (DE) Universität zu Köln DE Germany (DE) Robert Koch-Institut (RKI) DE Germany (DE) Charité - Universitätsmedizin Berlin DE Germany (DE) Auguste-Viktoria-Klinik DE Germany (DE) Klinikum Bayreuth DE Germany (DE) amedes Medizinische Dienstleistungen GmbH DE Germany (DE) Klinikum St. Georg DE Germany (DE)

How to cite

APA:

Kessel, J., Rossaert, A.C., Lingscheid, T., Grothe, J., Harrer, T., Wyen, C.,... Rickerts, V. (2024). Survival after cryptococcosis in Germany: A retrospective multicenter cohort study of patients diagnosed between 2004 and 2021. International Journal of Medical Microbiology, 314. https://doi.org/10.1016/j.ijmm.2024.151614

MLA:

Kessel, Johanna, et al. "Survival after cryptococcosis in Germany: A retrospective multicenter cohort study of patients diagnosed between 2004 and 2021." International Journal of Medical Microbiology 314 (2024).

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