Sequential changes in myocardial function after valve replacement for aortic stenosis by speckle tracking echocardiography
Rost C, Korder S, Wasmeier G, Wu M, Klinghammer L, Flachskampf FA, Daniel W, Voigt JU (2010)
Publication Type: Journal article
Publication year: 2010
Journal
Book Volume: 11
Pages Range: 584-589
Journal Issue: 7
DOI: 10.1093/ejechocard/jeq017
Abstract
Aims Regional myocardial function may change differently in different pathology. Speckle tracking echocardiography (STE) was applied to evaluate longitudinal, radial, and circumferential function in patients with aortic stenosis (AS) before, within 1 week, and 6 months after aortic valve replacement (AVR). Methods and results In 40 consecutive patients with severe AS, we acquired apical four-, three-, and two-chamber views and standard short-axis view pre- and post-AVR and after 6 months. Longitudinal, radial, and circumferential (LS, RS, and CS) were calculated by commercial STE software. Further, we analysed diastolic myocardial function by measuring E/e′ ratio. With AVR, valve area increased and remained stable at 6 months follow-up. Left ventricular mass was unchanged 1 week after AVR (270 ± 58 g vs. 267 ± 58 g, n.s.) but decreased significantly during the next 6 months (219 ± 50 g, P < 0.05). Left ventricular ejection fraction remained unchanged. Strain values did not change significantly within 1 week after AVR but increased significantly after 6 months (LS by 16, RS by 21, and CS by 28 of baseline values). E/e′ ratio was highly augmented before AVR (26.1 ± 12.5) and decreased significantly 6 months after AVR (15.9 ± 5.9). Conclusion Myocardial function significantly recovers after replacing the stenosed aortic valve. However, there is a considerable difference between the response of longitudinal, radial, and circumferential function. Our data suggest that echocardiographic assessment of regional function is feasible and of potential clinical importance. © The Author 2010.
Authors with CRIS profile
Lutz Klinghammer
Department of Medicine 2 – Cardiology and Angiology
Werner Daniel
Lehrstuhl für Innere Medizin II
Involved external institutions
Belgium (BE)How to cite
APA:
Rost, C., Korder, S., Wasmeier, G., Wu, M., Klinghammer, L., Flachskampf, F.A.,... Voigt, J.U. (2010). Sequential changes in myocardial function after valve replacement for aortic stenosis by speckle tracking echocardiography. European Journal of Echocardiography, 11(7), 584-589. https://doi.org/10.1093/ejechocard/jeq017
MLA:
Rost, Christian, et al. "Sequential changes in myocardial function after valve replacement for aortic stenosis by speckle tracking echocardiography." European Journal of Echocardiography 11.7 (2010): 584-589.
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