Hyperglycemia as a possible risk factor for mold infections - The potential preventative role of intensified glucose control in allogeneic hematopoietic stem cell transplantation

Fuji S, Loeffler J, Savani BN, Einsele H, Kapp M (2017)

Publication Type: Journal article, Review article

Publication year: 2017

Journal

Bone Marrow Transplantation Nature Publishing Group: Open Access Hybrid Model Option B

Book Volume: 52

Pages Range: 657-662

Journal Issue: 5

DOI: 10.1038/bmt.2016.306

Abstract

Diabetes mellitus (DM) is well-known as a disorder that increases the risk of infectious diseases. Various reports have shown that innate immunity is impaired in patients with DM, which is considered to be a major cause of increased risk of infectious diseases. However, there is a paucity of data about the actual risk of mold infections in patients with DM. Several treatment procedures, such as solid organ transplantation and hematopoietic stem cell transplantation (HSCT), are intrinsically associated with a high risk of mold infections and also correlated with an increased risk of post-transplant DM. Therefore, we could assume that organ transplant recipients or HSCT recipients with DM are at quite high risk of mold infections. Here, we aim to summarize the information about the increased risk of mold infections in patients with DM, and propose possible interventions such as intensive glucose control to reduce this risk in patients with DM.

Involved external institutions

National Cancer Centre Singapore (NCCS) SG Singapore (SG) Universitätsklinikum Würzburg DE Germany (DE) Vanderbilt University US United States (USA) (US)

How to cite

APA:

Fuji, S., Loeffler, J., Savani, B.N., Einsele, H., & Kapp, M. (2017). Hyperglycemia as a possible risk factor for mold infections - The potential preventative role of intensified glucose control in allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplantation, 52(5), 657-662. https://doi.org/10.1038/bmt.2016.306

MLA:

Fuji, Shigeo, et al. "Hyperglycemia as a possible risk factor for mold infections - The potential preventative role of intensified glucose control in allogeneic hematopoietic stem cell transplantation." Bone Marrow Transplantation 52.5 (2017): 657-662.

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