Primary leiomyosarcoma of the skin: a comprehensive review on diagnosis and treatment

Zacher M, Heppt MV, Brinker TJ, Hayani KM, Flaig MJ, Berking C (2018)

Publication Type: Journal article, Review article

Publication year: 2018

Journal

Medical Oncology Humana Press

Book Volume: 35

Article Number: 135

Journal Issue: 10

DOI: 10.1007/s12032-018-1196-2

Abstract

Sarcomas are a heterogeneous group of mesenchymal tumors which can affect bone and soft tissue. Leiomyosarcoma (LMS) is a rare subtype localized to the skin or subcutaneous tissue. Due to the heterogeneity of sarcomas, reviews and guidelines with an in-depth focus specifically on primary LMS of the skin are sparse. This article is intended to provide an up to date and systematic overview on diagnosis, treatment, and surveillance of this rare entity to provide a framework for decision making and management for dermato-oncologists. We discuss novel treatment options for advanced disease such as targeted therapy with kinase inhibitors and immune checkpoint blockade which may improve the prognosis even in advanced stages of LMS.

Authors with CRIS profile

Carola Berking

Involved external institutions

Ludwig-Maximilians-Universität (LMU) DE Germany (DE) Ruprecht-Karls-Universität Heidelberg DE Germany (DE)

How to cite

APA:

Zacher, M., Heppt, M.V., Brinker, T.J., Hayani, K.M., Flaig, M.J., & Berking, C. (2018). Primary leiomyosarcoma of the skin: a comprehensive review on diagnosis and treatment. Medical Oncology, 35(10). https://doi.org/10.1007/s12032-018-1196-2

MLA:

Zacher, Martina, et al. "Primary leiomyosarcoma of the skin: a comprehensive review on diagnosis and treatment." Medical Oncology 35.10 (2018).

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