Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes
Ndrepepa G, Schulz S, Neumann FJ, Laugwitz KL, Richardt G, Byrne RA, Poehler A, Kastrati A, Pache J (2014)
Publication Type: Journal article
Publication year: 2014
Journal
Book Volume: 10
Pages Range: 83-89
Journal Issue: 1
DOI: 10.4244/EIJV10I1A14
Abstract
Aims: The aim of this study was to assess the impact of bleeding after percutaneous coronary intervention (PCI) on the outcome of patients with type 2 diabetes. Methods and results: This study included 4,329 diabetic patients who underwent PCI. Bleeding was assessed using the Bleeding Academic Research Consortium criteria. The primary outcome was one-year mortality. Bleeding events occurred in 474 patients (10.9%). Access-site and non-access-site bleeds occurred in 274 patients (58%) and 200 patients (42%), respectively. Within the first year after PCI there were 198 deaths: 45 deaths (9.6%) among patients with bleeding and 153 deaths (4.0%) among patients without bleeding (adjusted hazard ratio=2.04 [95% confidence interval 1.38-3.00], p>0.001). There were 25 deaths (12.7%) among patients with non-access-site bleeding and 20 deaths (7.4%) among patients with access-site bleeding (odds ratio [OR]=3.45 [2.20-5.41], p>0.001 for non-access-site bleeding vs. no bleeding and OR=1.90 [1.17-3.01], p=0.008 for access-site bleeding vs. no bleeding). Bleeding improved the discriminatory power of the multivariable model for mortality prediction (p=0.002). Conclusions: In patients with diabetes undergoing PCI, occurrence of bleeding within the first 30 days after PCI was associated with a significant increase in the risk of one-year mortality. © Europa Digital & Publishing 2014. © Europa Digital & Publishing 2014.
Involved external institutions
Deutsches Herzzentrum München
Germany (DE)
Universitäts-Herzzentrum Freiburg - Bad Krozingen GmbH
Germany (DE)
Technische Universität München (TUM)
Germany (DE)
Segeberger Kliniken
Germany (DE)
Schön Kliniken
Germany (DE)
Germany (DE)
Universitäts-Herzzentrum Freiburg - Bad Krozingen GmbH
Germany (DE)
Technische Universität München (TUM)
Germany (DE)
Segeberger Kliniken
Germany (DE)
Schön Kliniken
Germany (DE)
How to cite
APA:
Ndrepepa, G., Schulz, S., Neumann, F.-J., Laugwitz, K.-L., Richardt, G., Byrne, R.A.,... Pache, J. (2014). Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes. EuroIntervention, 10(1), 83-89. https://doi.org/10.4244/EIJV10I1A14
MLA:
Ndrepepa, Gjin, et al. "Prognostic value of bleeding after percutaneous coronary intervention in patients with diabetes." EuroIntervention 10.1 (2014): 83-89.
BibTeX: Download