Tackling standardization in fluorescence molecular imaging
Koch M, Symvoulidis P, Ntziachristos V (2018)
Publication Type: Journal article
Publication year: 2018
Journal
Book Volume: 12
Pages Range: 505-515
Journal Issue: 9
DOI: 10.1038/s41566-018-0221-5
Abstract
The emerging clinical use of targeted fluorescent agents heralds a shift in intraoperative imaging practices that overcome the limitations of human vision. However, in contrast to established radiological methods, no appropriate performance specifications and standards have been established in fluorescence molecular imaging. Moreover, the dependence of fluorescence signals on many experimental parameters and the use of wavelengths ranging from the visible to short-wave infrared (400–1,700 nm) complicate quality control in fluorescence molecular imaging. Here, we discuss the experimental parameters that critically affect fluorescence molecular imaging accuracy, and introduce the concept of high-fidelity fluorescence imaging as a means for ensuring reliable reproduction of fluorescence biodistribution in tissue.
Involved external institutions
Germany (DE)How to cite
APA:
Koch, M., Symvoulidis, P., & Ntziachristos, V. (2018). Tackling standardization in fluorescence molecular imaging. Nature Photonics, 12(9), 505-515. https://doi.org/10.1038/s41566-018-0221-5
MLA:
Koch, Maximillian, Panagiotis Symvoulidis, and Vasilis Ntziachristos. "Tackling standardization in fluorescence molecular imaging." Nature Photonics 12.9 (2018): 505-515.
BibTeX: Download