360º optoacoustic capsule endoscopy at 50 Hz for esophageal imaging
Ali Z, Zakian C, Li Q, Gloriod J, Crozat S, Bouvet F, Pierre G, Sarantos V, Di Pietro M, Flisikowski K, Andersen P, Drexler W, Ntziachristos V (2022)
Publication Type: Journal article
Publication year: 2022
Journal
Book Volume: 25
Article Number: 100333
DOI: 10.1016/j.pacs.2022.100333
Abstract
Gastrointestinal (GI) endoscopy is a common medical diagnostic procedure used for esophageal cancer detection. Current emerging capsule optoacoustic endoscopes, however, suffer from low pulse repetition rates and slow scanning units limit attainable imaging frame rates. Consequently, motion artifacts result in inaccurate spatial mapping and misinterpretation of data. To overcome these limitations, we report a 360º, 50 Hz frame rate, distal scanning capsule optoacoustic endoscope. The translational capability of the instrument for human GI tract imaging was characterized with an Archimedean spiral phantom consisting of twelve 100 µm sutures, a stainless steel mesh with a pitch of 3 mm and an ex vivo pig esophagus sample. We estimated an imaging penetration depth of ~0.84 mm in vivo by immersing the mesh phantom in intralipid solution to simulate light scattering in human esophageal tissue and validated our findings ex vivo using pig esophagus. This proof-of-concept study demonstrates the translational potential of the proposed video-rate endoscope for human GI tract imaging.
Involved external institutions
Sonaxis SA
France (FR)
Technische Universität München (TUM)
Germany (DE)
Medizinische Universität Wien
Austria (AT)
Statice France
France (FR)
Rayfos Ltd.
United Kingdom (GB)
University of Cambridge
United Kingdom (GB)
Technical University of Denmark / Danmarks Tekniske Universitet (DTU)
Denmark (DK)
France (FR)
Technische Universität München (TUM)
Germany (DE)
Medizinische Universität Wien
Austria (AT)
Statice France
France (FR)
Rayfos Ltd.
United Kingdom (GB)
University of Cambridge
United Kingdom (GB)
Technical University of Denmark / Danmarks Tekniske Universitet (DTU)
Denmark (DK)
How to cite
APA:
Ali, Z., Zakian, C., Li, Q., Gloriod, J., Crozat, S., Bouvet, F.,... Ntziachristos, V. (2022). 360º optoacoustic capsule endoscopy at 50 Hz for esophageal imaging. Photoacoustics, 25. https://doi.org/10.1016/j.pacs.2022.100333
MLA:
Ali, Zakiullah, et al. "360º optoacoustic capsule endoscopy at 50 Hz for esophageal imaging." Photoacoustics 25 (2022).
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