COVID-19 Infections in Adults with Congenital Heart Disease—A Prospective Single-Center Study in an Outpatient Setting
Langes N, Meierhofer C, Nagdyman N, Maurer SJ, Bourier F, Halle M, Holdenrieder S, Ewert P, Tutarel O (2022)
Publication Type: Journal article
Publication year: 2022
Journal
Book Volume: 11
Article Number: 6105
Journal Issue: 20
DOI: 10.3390/jcm11206105
Abstract
Background: COVID-19 might pose a risk for adults with congenital heart disease (ACHD). However, data regarding the rate of infection as well as myocardial involvement in ACHD patients are currently lacking. Methods: During the study period from January to June 2021, all consecutive outpatients from our ACHD clinic were eligible to participate. Clinical data were collected. An antibody test for COVID-19 was performed in all patients. Cardiovascular magnetic resonance imaging (CMR) was offered to those with a positive antibody test. Results: Overall, 420 patients (44.8% female, mean age 36.4 ± 11.6 years) participated. Congenital heart defect (CHD) complexity was simple in 96 (22.9%), moderate in 186 (44.3%), complex in 117 (27.9%), and miscellaneous in 21 (5.0%) patients. Altogether, 28 (6.7%) patients had a positive antibody test. Out of these, 14 had an asymptomatic course. The others had mainly mild symptoms and were managed as outpatients. Furthermore, 11 patients (39.3%) had even not been aware of their infection. Fourteen patients underwent a CMR without signs of myocardial involvement in any of them. Conclusions: We observed a number of undetected cases of COVID-19 infections in our ACHD population. Reassuringly, in all cases, the infection had a mild clinical course.
Involved external institutions
Germany (DE)How to cite
APA:
Langes, N., Meierhofer, C., Nagdyman, N., Maurer, S.J., Bourier, F., Halle, M.,... Tutarel, O. (2022). COVID-19 Infections in Adults with Congenital Heart Disease—A Prospective Single-Center Study in an Outpatient Setting. Journal of Clinical Medicine, 11(20). https://doi.org/10.3390/jcm11206105
MLA:
Langes, Nora, et al. "COVID-19 Infections in Adults with Congenital Heart Disease—A Prospective Single-Center Study in an Outpatient Setting." Journal of Clinical Medicine 11.20 (2022).
BibTeX: Download