Applicability and discriminative value of a semiautomatic three-dimensional spherical volume for the assessment of the apparent diffusion coefficient in suspicious breast lesions—feasibility study
Hering J, Laun FB, Lederer W, Daniel H, Kuder TA, Stieber A, Delorme S, Maier-Hein KH, Schlemmer HP, Bickelhaupt S (2016)
Publication Type: Journal article
Publication year: 2016
Journal
Book Volume: 40
Pages Range: 1280-1285
Journal Issue: 6
DOI: 10.1016/j.clinimag.2016.08.022
Abstract
Introduction To evaluate the feasibility and accuracy of a semiautomatic, three-dimensional volume of interest (3D sphere) for measuring the apparent diffusion coefficient (ADC) in suspicious breast lesions compared to conventional single-slice two-dimensional regions of interest (2D ROIs). Method This institutional-review-board-approved study included 56 participants with Breast Imaging Reporting and Data System 4/5 lesion. All received diffusion-weighted imaging magnetic resonance imaging prior to biopsy (b=0–1500 s/mm2). ADC values were measured in the lesions with both methods. Reproducibility and accuracies were compared. Results Area under the curve was 0.93 [95% confidence interval (CI) 0.86–0.99] for the 3D sphere and 0.91 (95% CI 0.84–0.98) for the 2D ROIs without significantly differing reproducibility (P=.45). Conclusion A semiautomatic 3D sphere could reliably estimate ADC values in suspicious breast lesions without significant difference compared to conventional 2D ROIs.
Authors with CRIS profile
Involved external institutions
Deutsches Krebsforschungszentrum (DKFZ)
Germany (DE)
ATOS-Praxisklinik Heidelberg
Germany (DE)
RadiologieZentrum Mannheim
Germany (DE)
Universitätsklinikum Heidelberg
Germany (DE)
Germany (DE)
ATOS-Praxisklinik Heidelberg
Germany (DE)
RadiologieZentrum Mannheim
Germany (DE)
Universitätsklinikum Heidelberg
Germany (DE)
How to cite
APA:
Hering, J., Laun, F.B., Lederer, W., Daniel, H., Kuder, T.A., Stieber, A.,... Bickelhaupt, S. (2016). Applicability and discriminative value of a semiautomatic three-dimensional spherical volume for the assessment of the apparent diffusion coefficient in suspicious breast lesions—feasibility study. Clinical Imaging, 40(6), 1280-1285. https://doi.org/10.1016/j.clinimag.2016.08.022
MLA:
Hering, Jan, et al. "Applicability and discriminative value of a semiautomatic three-dimensional spherical volume for the assessment of the apparent diffusion coefficient in suspicious breast lesions—feasibility study." Clinical Imaging 40.6 (2016): 1280-1285.
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